House Spoilers: Medical Mystery

What could be the medical mystery in the Season 6 Premiere of House, M.D.?

From Mickey O'Connor of TV Guide:

Any scoop on House? I'm concerned that House's incarceration is going to ruin the show. — Deb S.

MICKEY: Good news for some of you — no Thirteen in the season premiere! More good news: House's Cuckoo's Nest routine is infinitely entertaining. The much-spoiled trip to the carnival is surprisingly more touching than I'd imagined. In the Heights' Lin-Manuel Miranda and Andre Braugher are both fantastic. As an added bonus, just because he's a patient doesn't mean there isn't a mystery to solve.

Here's another House Season 6 Premiere Promo for all of you House fans. Another mystery here is the reason why Taub wants out of the fellowship team. Is he the one who gets axed from the show? I wonder . . .